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HIV/HCV Coinfection

Risk factors for severe liver fibrosis identified

Published in Hepatitis Weekly, April 26th, 2004

Risk factors for severe liver fibrosis have been identified for HIV patients with chronic hepatitis C.

According to researchers in Spain, a "study was performed in 10 European health care centers in which 914 patients coinfected with hepatitis C virus (HCV) and human immunodeficiency virus (HIV) who had elevated serum alanine aminotransferase (ALT) levels underwent liver biopsy during the period of 1992 through 2002.

"Overall, the METAVIR liver fibrosis stage was F0 in 10% of patients, F1 in 33%, F2 in 22%, F3 in 22%, and F4 in 13%," reported L. Martin-Carbonero and coauthors at Carlos III Hospital in Madrid.

"Predictors of severe...

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