Psychology
Indoleamine 2,3-dioxygenase plays a role in interferon-alpha-induced depression
Published in Hepatitis Weekly, May 10th, 2004
According to a study from the Netherlands, "the mechanisms by which administration of interferon-alpha induces neuropsychiatric side effects, such as depressive symptoms and changes in cognitive function, are not clear as yet. Direct influence on serotonergic neurotransmission may contribute to these side effects.
"In addition, the enzyme indoleamine 2,3-dioxygenase (IDO), which converts tryptophan into kynurenine, may play an important role, first, because IDO activation leads to reduced levels of tryptophan, the precursor of serotonin (5-HT), and thus to reduced...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Hepatitis Weekly
Source: Hepatitis Weekly (2004-05-10)
More Articles from Hepatitis Weekly
- Drug Development
Murine hepatitis models can screen for Cav 1.3-specific therapy - Liver Cancer Therapy
Vesicular stomatitis virus infusions staunch hepatocellular carcinoma in rats - Microbiology
Autoimmune liver disease patients show evidence of Helicobacter infection - Oncogenesis
Hepatitis B virus preS1 sequences stimulate squamous cell carcinoma antigen - Oncogenesis
Specific hepatitis B virus mutations predict liver cancer formation - Adverse Drug Effects
Interferon-alpha stimulates optic neuropathy in a chronic hepatitis C patient - More from this issue of Hepatitis Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
