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Liver Cancer Therapy

Vesicular stomatitis virus infusions staunch hepatocellular carcinoma in rats

Published in Hepatitis Weekly, May 10th, 2004

Vesicular stomatitis virus infusions staunch hepatocellular carcinoma in rats.

According to a study from the United States, "hepatocellular carcinoma (HCC) is a lethal malignancy with poor prognosis and few effective treatments, as well as ever-increasing frequencies in the Western world. Viruses that replicate selectively in cancer cells hold considerable promise as novel therapeutic agents for the treatment of malignancy. Vesicular stomatitis virus (VSV) is a negative-strand RNA virus with intrinsic oncolytic specificity due to significantly attenuated antiviral responses in many tumor cells.

"The aim of this study was to evaluate the potential of...

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