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Transplantation Medicine

LEA29Y may provide new option for preventing organ rejection

Published in Hepatitis Weekly, June 14th, 2004

An investigational treatment called LEA29Y may represent a less toxic way to preserve transplanted kidney function and improve patient outcomes, according to new data presented at the American Transplant Congress.

More than 20 leading transplant centers in the U.S., Canada, and Europe, including Emory University, participated in a phase II study comparing LEA29Y, also known as BMS-224818, to a similar regimen containing standard therapy with cyclosporine.

Study results showed that 6 months following kidney transplant, LEA29Y was as effective as standard therapy with cyclosporine in preventing acute rejection. However, LEA29Y-treated patients...

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