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Immunology

Hepatitis C virus clears despite immunosuppression after liver transplantation

Published in Hepatitis Weekly, June 28th, 2004

Hepatitis C virus clears despite immunosuppression after liver transplantation.

According to a study from Spain, "recurrent hepatitis C virus (HCV) infection after liver transplantation is universal and sustained clearance of HCV-RNA rarely occurs. The aim of this study was to characterize cell-mediated immunity and cytokine production in HCV-infected patients after liver transplant."

"The study included 6 pretransplantation patients (PT) and 15 liver transplanted patients, including 5 with spontaneous HCV-RNA clearance (SC group), 5 with sustained virological response after antiviral treatment (SVR group), and 5 with no response (NR group)."

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