Chronic Liver Disease
Viral protein drives lymphocyte recruitment in hepatitis C transgenic mice
Published in Hepatitis Weekly, August 23rd, 2004
"To assess the effects of constitutive hepatitis C virus (HCV) gene expression on liver, transgenic mice carrying the entire HCV open reading frame inserted in the alpha1 antitrypsin (All AT) gene were generated. Expression of A1AT/HCV mRNA was found to be mainly limited to perivascular areas of the liver as indicated by in situ hybridization analysis. HCV core protein was detected in Western blots of liver extracts, whereas the expression of E2, NS3 and NS5 proteins was revealed by immunostaining of liver samples using HCV-specific antisera," scientists writing in the Journal of General...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Hepatitis Weekly
Source: Hepatitis Weekly (2004-08-23)
More Articles from Hepatitis Weekly
- Chronic Hepatitis C
Consensus interferon and lactoferrin don't improve hepatitis C response rates - Diagnostics
Short-term hepatitis C virus infections reveal novel epitopes - Pediatric Cancer
HCV-associated liver disease in young cancer survivors shadows adult illness - Zoonotic Disease
Avian hepatitis E virus shares the features of swine and human HEV - Adverse Side Effects
Pegylated interferon causes dystonia in some patients infected with hepatitis B - Antiretroviral Therapy
Antiretroviral emtricitabine (FTC) has low toxicity in HIV-infected patients - More from this issue of Hepatitis Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
