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Genotypic Analysis

The NS5b region of hepatitis C virus is more accurate for determining subtypes

Published in Hepatitis Weekly, August 23rd, 2004

The NS5b region of hepatitis C virus is more accurate for determining subtypes.

According to a study from France, "hepatitis C virus (HCV) strains isolated from 68 hemodialysis Tunisian patients exhibiting chronic infection were genotyped targeting the NS5b region of the HCV genome using a prototype assay developed by Bayer HealthCare-Diagnostics (TRUGENE NS5b HCV). The overall results were compared to those obtained with another assay of the same company based on sequencing of the 5' non-coding region (TRUGENE HCV 5'NC genotyping kit). All strains could be typed by the 5'NC typing kit, but only 62 (91.2%) by the NS5b prototype assay."

"All the 62...

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