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Antiretroviral Therapy

Antiretroviral emtricitabine (FTC) has low toxicity in HIV-infected patients

Published in Hepatitis Weekly, August 23rd, 2004

The antiretroviral therapy emtricitabine (FTC) has low toxicity in HIV-infected patients.

"Emtricitabine (FTC) is a synthetic nucleoside analogue of cytosine, which is intracellularly phosforylated to form the active form erntricitabine 5'-triphosphate (E5TP).

"E5TP inhibits both HIV and Hepatitis B reverse transcriptase. Clinical trials have shown FTC to be active as part of highly active anti-retroviral therapy in naive HIV-positive patients," researchers in England report.

"FTC may be dosed once daily and in vitro is less associated with the M184V mutation, which is classically associated with failure of treatment with...

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