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Hepatitis B Vaccine

Hepatitis B vaccine plus lamivudine did not eliminate viral DNA

Published in Hepatitis Weekly, August 30th, 2004

Combined recombinant hepatitis B vaccine and lamivudine therapy did not eliminate viral DNA in a patient with chronic hepatitis B.

"We report the first case of a woman having chronic hepatitis B treated with a combination therapy of recombinant hepatitis B vaccine and lamivudine for 18 months. The main aims of such a combined therapy were to assess whether the concomitant anti-hepatitis B virus (HBV) vaccination might prevent the emergence of a mutant HBV and lead to sustained hepatitis B e antigen seroconversion with undetectable serum HBV DNA," scientists in Turkey report.

"The data from the present case demonstrated that combination of anti-HBV...

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