Immunology

Fetal stem cells transfer to and remain in maternal bone and bone marrow

Published in Hepatitis Weekly, August 30th, 2004

Fetal mesenchymal stem cells transfer into and remain in maternal bone and bone marrow for the rest of the mother's life, according to a study from the United Kingdom.

"Fetal cells enter maternal blood during pregnancy and persist in women with autoimmune disease. The frequency of subsequent fetomaternal microchimerism in healthy women and its cell type is unknown," said K. O'Donoghue and colleagues, University of London Imperial College of Science, Technology, and Medicine.

Microchimerism is the presence of donor or fetal cells that remain in the graft recipient or mother, respectively, and cannot be detected by flow cytometry. Microchimerism can be...

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Source: Hepatitis Weekly (2004-08-30)

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