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Dried blood samples are useful for analyzing hepatitis B virus DNA

Published in Hepatitis Weekly, September 13th, 2004

Dried blood samples are useful for analyzing hepatitis B virus DNA.

According to new research from Spain, "the purpose of this study was to assess the use of dried blood spot (DBS) samples for hepatitis B virus (HBV) DNA quantification, HBV genotyping, and detection of G1896A precore mutants and variants in the YMDD polymerase motif."

"We studied DBS and serum samples from 82 patients with chronic HBV infection (23 hepatitis B e antigen [HBeAg]positive and 39 HBeAg-negative), 20 HBeAg-inactive carriers, and 15 HBeAg-negative patients under lamivudine therapy (selected from chronic HBV patients). DBS samples consisted of approximately 20 mcL of blood...

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