Acute Liver Failure
Indomethacin reduces intracranial pressure in ALF patients
Published in Hepatitis Weekly, September 13th, 2004
Uncontrolled ICP elevation "continues to be one of the most significant causes of early death" in ALF patients, scientists in Denmark explained.
In a recent study, F. Tofteng and colleagues at the University of Copenhagen "aimed to determine the effects of indomethacin on ICP and cerebral perfusion pressure in 12 patients with ALF and brain edema (9 females/3 males, median age 49.5 (range 21 to 64) yrs.)."
In addition, "changes in cerebral perfusion determined by transcranial Doppler technique (Vmean ) and jugular bulb...
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Source: Hepatitis Weekly (2004-09-13)
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