Immunology
Natural killer cell interactions govern immunity to hepatitis C virus
Published in Hepatitis Weekly, September 20th, 2004
According to a study from England, "natural killer (NK) cells provide a central defense against viral infection by using inhibitory and activation receptors for major histocompatibility complex class I molecules as a means of controlling their activity. We show that genes encoding the inhibitory NK cell receptor KIR2DL3 and its human leukocyte antigen C group1 (HLA-C1) ligand directly influence resolution of hepatitis C virus (HCV) infection."
"This effect was observed in Caucasians and African Americans with expected low infectious doses of HCV but not in those with high-dose...
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Source: Hepatitis Weekly (2004-09-20)
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