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Hepatitis Vaccine

Enrollment complete for phase II/III hepatitis B prophylactic vaccine trial

Published in Hepatitis Weekly, September 27th, 2004

Dynavax Technologies Corp. (DVAX), has completed enrollment and administered the first round of immunizations in a phase II/III clinical trial of its hepatitis B (HBV) prophylactic vaccine candidate containing Dynavax's Immunostimulatory Sequence.

The study, being conducted at two study centers in Singapore, began enrollment in June 2004.

The double-blind study compares Dynavax's HBV vaccine candidate with GlaxoSmithKline's marketed HBV vaccine, Engerix-B, in 94 subjects. The subjects, ranging between 40-70 years of age, had not previously been immunized against HBV. The full immunization schedule will consist of three injections over 6 months, with...

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