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Adverse Drug Effects

Pegylated interferon may cause vision disorders in chronic hepatitis C patients

Published in Hepatitis Weekly, October 25th, 2004

Pegylated interferon may cause vision disorders in chronic hepatitis C patients.

"Ocular toxicity, including retinopathy, optic neuropathy and ocular loss, has been infrequently (<1%) reported as a potentially serious adverse event associated with standard interferon therapy. The new pegylated interferons have improved pharmacokinetics which translates to better antiviral efficacy, however, this improved pharmacokinetic profile also has the potential to alter the frequency and extent of their adverse events," according to researchers in the United States.

"We describe a case of chronic hepatitis C infection that developed visual complaints after 1...

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