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Hepatitis Weekly

Susan Hasty, Publisher

Table of Contents . . . November 1st, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Hepatitis Weekly | Other Publications

Cancer Risk Factor - Hepatitis B virus core promoter mutations prevail in liver cancer

Chronic Hepatitis B - Lamivudine does not improve the response of hepatitis B to peginterferon

Diagnostics - Total HCV core antigen assay detects early infection but not viral elimination

Hematology - A new magnetic extraction method uncovers HCV status in hemodialysis patients

Liver Cancer - Patients with hepatic fibrosis and hepatitis C need broader cancer screenings

Adverse Drug Effects - Combination therapy for liver cancer is linked to interstitial pneumonia

Angiology - Microvascular dysfunction encourages the progression of steatohepatitis in mice

Antiviral Therapy - RANTES haplotypes influence the response to chronic hepatitis C therapy

Autoimmune Disease - Antinuclear antibody absorption by hepatitis B vaccine warrants evaluation

Bacteriology - Swedish company presents mass screening tests at investment conference

Blood Safety - Chiron announces blood-screening licensing agreement

Business Update - Agreement signed for distribution of bacterial detection system in Japan

Cancer Research - Companies announce filing of MAA in Europe to inject anticancer drug for MDS

Cancer Treatment - Scientists develop new drugs that improve survival after bone marrow transplant

Chronic Hepatitis B - Estrogen receptor alpha genotypes associate with susceptibility to hepatitis B

Chronic Hepatitis B - Real-time PCR and melting curve analysis offer rapid assessments of hepatitis B

Chronic Liver Disease - Serum hepatitis B virus strains parallel hepatic strains in acute exacerbations

Chronic Liver Disease - Site-specific keratin hyperphosphorylation marks liver disease progression

Cirrhosis - Epivir-HBV delays liver complications from chronic hepatitis B

Disease Associations - Immune restoration disease arises in association with antiretroviral therapy

Drug Development - Biotechnology company files a request of re-examination of Benitec

Drug Development - Pharmaceutical receives U.S. FDA approval of GI disease and hepatitis drugs

Environmental Health - Gene profiling can be used to distinguish toxicant classes

Food Safety - Food-borne illness strikes at least 2 billion people a year

Hepatitis - Drug development company announces hepatitis C study presented at conference

Hepatitis - Study reports results of PegIntron and Rebetol combination therapy for hepatitis

Hepatitis A Virus - British Columbia wine festival may affect Hepatitis A exposure

Hepatitis B Virus - Abstract describing remofovir study results posted to AASLD web site

Hepatitis C Virus Infection - Persistence of hepatitis C virus associated with human leukocyte antigen class 1

Hepatitis/HIV Coinfection - FDA grants priority review to Pegasys with Copegus for HCV in HIV patients

Hepatocellular Carcinoma - Gene expression patterns with prognostic value identified

Hepatology - Novel peptide-based vaccines generate immunity to hepatotropic pathogens

Hepatology - PPARalpha regulates male-specific hepatic P450 in mice

Hepatology - Patients with liver disease have lower levels of circulating dendritic cells

Hepatology - Prognosis and treatment of hepatorenal syndrome reviewed

Immunology - Dendritic cells in chronic hepatitis C patients alter immunological response

Legal Issues - Judge says Nebraska liable for bulk of any successful hepatitis lawsuits

Liver Cancer - CD44v3 predicts the risk of hepatocellular carcinoma distant metastasis

Liver Cancer - Estrogen plays a critical role in female hepatocarcinogenesis

Liver Necrosis - Plasma osteopontin levels rise in patients diagnosed with fulminant hepatitis

Mutagenesis - PCR-RFLP is quick and reliable for detecting hepatitis B virus core mutants

Osteoporosis - Ribavirin impairs osteoblast proliferation and differentiation in lab cultures

Oxygen Therapy - Update provided on revised Oxygent development plan

Stem Cell Transplantation - Pre-allogeneic SCT is not associated with increased hypercoagulability

Transplant Medicine - Iron levels in donor livers associate with fibrosis in female graft recipients

Transplant Medicine - Portal venous, hepatic arterial reperfusion interval influence graft impairment

Transplantation Medicine - Newer drugs target recurrent hepatitis B after liver transplantation

Vaccine Development - Novel vaccine containing hepatitis C E1 protein shows promise in volunteers

Vaccines - Study finds demand for vaccines in U.S. will increase 8.6% annually

Viral Hepatitis - Hepatitis B superinfection cannot restore hepatitis C-specific CD8 reactivity

Virology - Estimates of hepatitis E virus mutagenesis produce alluring data

Virology - Host immunology and genomics govern hepatitis C virus progression

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