Cancer Risk Factor
Hepatitis B virus core promoter mutations prevail in liver cancer
Published in Hepatitis Weekly, November 1st, 2004
"The role of hepatitis B virus (HBV) genotypes, core promoter (CP) and precore mutants on hepatocellular carcinoma (HCC) is still controversial. We aimed to determine their role on the development and clinical features of HCC. HBV genotypes and CP/precore mutations were determined in 90 HCC patients and 180 matched control patients," scientists in the Peoples Republic of China report.
"In the 90 HCC patients, 22 (24.4%) and 68 (75.6%) had subtype Ba and genotype C, respectively. The prevalence of genotype C and CP mutations was significantly higher in HCC patients compared with...
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Source: Hepatitis Weekly (2004-11-01)
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