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Liver Transplantation

Epidural analgesia may contribute to abnormal coagulation in liver donors

Published in Hepatitis Weekly, November 8th, 2004

Epidural analgesia may contribute to abnormal coagulation in liver donors.

"The risks and benefits of adult-to-adult living donor liver transplantation need to be carefully evaluated. Anesthetic management includes postoperative epidural pain relief; however, even patients with a normal preoperative coagulation profile may suffer transient postoperative coagulation derangement," surgeons in Italy explained.

In a recent study, A. Siniscalchi and coauthors at the University of Modena examined "the possible causes of postoperative coagulation derangement after donor hepatectomy and the possible implications on epidural analgesia."

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