Chronic Hepatitis C

Combination therapy lowers high hepatitis C viremia slowly

Published in Hepatitis Weekly, November 15th, 2004

Combination therapy lowers high hepatitis C viremia slowly.

"This study aimed to find how ribavirin increases viral disappearance in patients with hepatitis C virus (HCV) of genotype 1 and high baseline viral loads (>5.0 x10⁵ copies/mL) when given with interferon (IFN). Using the real-time quantitative polymerase chain reaction, we measured serum HCV in 20 patients during the first 12 weeks of therapy with IFN-alpha2b and ribavirin. Controls were 10 similar patients given IFN-alpha2b alone," researchers in Japan report.

"IFN-alpha2b was given at 6 MU daily for 2 weeks, and then 3 times weekly. Ribavirin was given at 600 or 800 mg daily....

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Source: Hepatitis Weekly (2004-11-15)

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