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Chronic Liver Disease

Biochemical tests could supplant liver biopsies for diagnosing liver fibrosis

Published in Hepatitis Weekly, November 22nd, 2004

Biochemical tests could supplant liver biopsies for diagnosing liver fibrosis.

"Laboratory tests for the noninvasive diagnosis of liver fibrosis were studied extensively in the past. However, no test is yet accepted to replace liver biopsy as the gold standard. The establishment of widely accepted semiquantitative histologic scoring systems for the grading and staging of chronic liver disease (e.g, Ishak, Metavir and Scheuer) was paralleled by a significant upturn of research in circulating markers of liver fibrosis," scientists writing in the journal Expert Review of Molecular Diagnostics state.

"We are now experiencing the renaissance of...

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