Diagnostics
Core antigen assay can't confirm active hepatitis C virus infection
Published in Hepatitis Weekly, November 22nd, 2004
According to a study from Canada, "the British Columbia Center for Disease Control laboratory performs approximately 95% of all hepatitis C virus (HCV) antibody tests for the province's 4 million inhabitants. In 2002, the laboratory tested 96,000 specimens for anti-HCV antibodies, of which 4,800 (5%) were seroreactive and required confirmation of active infection."
"Although HCV RNA assays with a sensitivity of 50 IU/mI or less are recommended for the confirmation of active HCV infection, given the large number of seroreactive specimens tested annually, we evaluated the Ortho trak-C assay...
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Source: Hepatitis Weekly (2004-11-22)
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