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Oncology

KL-6 is a serological marker for liver cancer in patients with hepatitis C

Published in Hepatitis Weekly, November 22nd, 2004

KL-6 is a serological marker for liver cancer in patients with hepatitis C.

According to researchers in Japan, "we investigated the clinical significance of serum and intrahepatic KL-6/MUC1 (KL-6) in patients with hepatitis C virus (HCV) antibody-positive hepatocellular carcinoma (HCC). The subjects included 76 patients diagnosed with anti-HCV positive HCC, 69 with, and 51 without, liver cirrhosis (LC). Frozen serum samples were obtained from each subject to determine the serum KL-6 levels using an enzyme-linked immunosorbent assay."

"Expression of KL-6 antigen in the liver was also investigated using immunoperoxidase staining. The mean serum KL-6...

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