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Injection drug users often develop hepatitis C virus superinfections

Published in Hepatitis Weekly, November 22nd, 2004

Injection drug users often develop hepatitis C virus superinfections.

"The frequency of hepatitis C virus (HCV) superinfection with a divergent viral strain was determined in a cohort of recently infected young injection drug users (IDUs) with an HCV incidence rate of 25%. HCV was amplified, by use of polymerase chain reaction (PCR), from plasma samples collected from 25 HCV-infected individuals over an average period of 12 months, and their viral sequences were compared," wrote investigators in the United States.

"Phylogenetic analysis identified 5 IDUs with superinfection (20%) occurring after seroconversion: 2 IDUs were superinfected with...

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