Adverse Drug Effects
Interferon alfa causes vitiligo and psoriasis in a patient with hepatitis B
Published in Hepatitis Weekly, November 29th, 2004
According to a study from Turkey, "well-known cutaneous side effects of interferon (IFN)-alfa therapy include dry skin, pruritus, hair loss, and psoriasis. Presumably because of its potent immunomodulatory activity, the use of IFN-alfa has also led to the development of autoimmune diseases in susceptible individuals. Vitiligo, an autoimmune cutaneous disease, has been reported to occur during IFN-alfa therapy."
"We report a 10-year-old girl with chronic hepatitis B infection in whom IFN-alfa treatment induced de novo development of vitiligo and psoriasis." wrote D. Seckin...
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Source: Hepatitis Weekly (2004-11-29)
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