Hepatology
Beta2 -glycoprotein I inhibits liposome uptake by liver cells
Published in Hepatitis Weekly, March 7th, 2005
"Adsorption of serum proteins to the liposomal surface plays a critical role in liposome clearance from the blood," scientists in the Netherlands explained.
X. Yan and colleagues at the University of Groningen conducted a study "to investigate the role of liposome-adsorbed serum proteins in the interaction of liposomes with hepatocytes."
"We analyzed the serum proteins adsorbing to the surface of differently composed small unilamellar liposomes during incubation with human or rat serum, and found that one protein, with a...
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Source: Hepatitis Weekly (2005-03-07)
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