Published in Hepatitis Weekly, March 7th, 2005
"PU.1 is a member of the ETS family of transcription factors and is required for the development of multiple hematopoietic lineages. PU.1-/- mice die from hematopoietic failure at about embryonic day 18.5 (e18.5) and show a complete absence of B cells, mature T cells, and macrophages.
"To investigate the role of PU.1 in the regulation of HSCs," wrote H.G. Kim...
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