Chronic Liver Disease
Mitochondrial defects prevail in liver disease and liver graft dysfunction
Published in Hepatitis Weekly, March 14th, 2005
"The mitochondria play a crucial role in maintaining hepatocyte integrity and functions. Mitochondrial defects are either inherited or acquired. Mitochondria dysfunction occurs when the hepatocyte experience excessive physiologic stress," researchers in the United States advise.
"Its clinical presentation depends on the severity of the stress. It varies from mild abnormalities in liver biochemical tests to manifestations of acute or chronic liver failure," said T. Hassanein and colleagues, University of California San Diego, School of Medicine.
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Source: Hepatitis Weekly (2005-03-14)
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