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Hepatotoxicity

The DDW-J scale categorizes drug-induced liver injury with accuracy

Published in Hepatitis Weekly, March 14th, 2005

The DDW-J scale diagnoses drug-induced liver injury with accuracy.

"There are no specific diagnostic markers for drug-induced liver injury (DILI), a disease that is unpredictable and occasionally fatal. A new diagnostic scale, the DDW-J scale, was recently proposed in Japan, by modifying the International Consensus Meeting (ICM) scale in the items concerning chronologic criteria, concomitant drug(s), and extrahepatic manifestations," researchers in Japan report.

"In order to determine the validity of the DDW-J scale, we assessed 127 patients (81 patients with DILI and 46 control patients) received a total of 423 drugs," said M. Watanabe and...

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