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Virology

Recent studies add new data to virology research

Published in Hepatitis Weekly, March 14th, 2005

Investigators in the United States, Italy and France have published new virology data.

Study 1: Hepatitis delta virus antigen methylation guides localization and replication.

"Hepatitis delta virus (HDV) contains a circular RNA which encodes a single protein, hepatitis delta antigen (HDAg). HDAg exists in two forms, a small form (S-HDAg) and a large form (L-HDAg). S-HDAg can transactivate HDV RNA replication," scientists in the United States report.

"Recent studies have shown that post-translational modifications, such as phosphorylation and acetylation, of S-HDAg can modulate HDV RNA replication. Here we show that S-HDAg can be...

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