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Chronic Hepatitis B

Screenings for hepatitis B antigen predict treatment response to lamivudine

Published in Hepatitis Weekly, April 11th, 2005

Screenings for hepatitis B antigen predict treatment response to lamivudine.

According to a report from South Korea, "the aim of this study was to determine whether the changing patterns of quantitative hepatitis B e antigen (HBeAg) levels by serial monitoring could predict HBeAg seroconversion and viral breakthrough during lamivudine therapy. We retrospectively analyzed 340 HBeAg positive naive chronic hepatitis B patients treated with lamivudine. The mean duration of lamivudine therapy was 18.7 (range 6-56) months."

"The changing patterns and reduction rates of pretreatment HBeAg levels by serial monitoring were categorized into three groups:...

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