HIV/AIDS Therapy
Chronic viral hepatitis alters the pharmacokinetics of antiretroviral therapy
Published in Hepatitis Weekly, May 2nd, 2005
"Chronic viral hepatitis is common among persons with HIV- 1 infection, because of shared modes of transmission, and coinfection results in accelerated liver damage, compared with persons with chronic viral hepatitis alone. The use of highly active antiretroviral therapy (HAART) has led to a significant decrease in the morbidity and mortality associated with HIV- 1 infection," scientists writing in the journal Clinical Infectious Diseases report.
"A number of the medications that are commonly used in HAART regimens are metabolized by the hepatic CYP enzymes, which...
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Source: Hepatitis Weekly (2005-05-02)
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