Published in Hepatitis Weekly, May 2nd, 2005
"Using high-density oligonucleotide array, we comprehensively analyzed expression levels of 12,600 genes in 50 hepatocellular carcinoma (HCC) samples with positive hepatitis C virus (HCV) serology (well (G1), moderately (G2), and poorly (G3) differentiated tumors) and 11 non-tumoros livers (L1 and L0) with and without HCV infection, " scientists in Japan report.
"We searched for discriminatory genes of transition (L0 vs. L1, L1 vs.G1, G1 vs. G2, G2 vs. G3) with a supervised learning method, and then arranged the samples by self-organizing map (SOM) with the discriminatory gene sets. The SOM...
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