Chronic Liver Disease
Platelet-derived growth factor C initiates liver disease in animal models
Published in Hepatitis Weekly, May 16th, 2005
"Members of the platelet-derived growth factor (PDGF) ligand family are known to play important roles in wound healing and fibrotic disease. We show that both transient and stable expression of PDGF-C results in the development of liver fibrosis consisting of the deposition of collagen in a pericellular and perivenular pattern that resembles human alcoholic and nonalcoholic fatty liver disease," investigators in the United States report.
"Fibrosis in PDGF-C transgenic mice, as demonstrated by staining and hydroxyproline content, is preceded by activation and proliferation of...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Hepatitis Weekly
Source: Hepatitis Weekly (2005-05-16)
More Articles from Hepatitis Weekly
- Diagnostics
Optical fiber immunosensor detects antibodies to hepatitis C virus antigen - Liver Cancer
Mutant p53 allows hepatitis C virus core-expressing cells to develop cancer - Liver Transplantation
A simple noninvasive index predicts fibrosis in HCV-infected liver recipients - Stem Cell Research
Stem cell transplantation reactivates resolved hepatitis B infection - Transplant Medicine
Mcm-2 predicts fibrosis progression after HCV-related liver transplantation - Addiction Medicine
Medical exams before drug abuse treatment open avenues for hepatitis screening - More from this issue of Hepatitis Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
