Gastroenterology
Primary human hepatocytes repopulate the livers of chimeric mice
Published in Hepatitis Weekly, May 23rd, 2005
"A small animal model harboring a functional human liver cell xenograft would be a useful tool to study human liver cell biology, drug metabolism, and infections with hepatotropic viruses. Here we describe the repopulation, organization, and function of human hepatocytes in a mouse recipient and the infections with hepatitis B virus (HBV) and hepatitis C virus (HCV) of the transplanted cells," scientists in Belgium report.
"Homozygous urokinase plasminogen activator (uPA)-SCID mice underwent transplantation with primary human hepatocytes, and at different times animals were bled and...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Hepatitis Weekly
Source: Hepatitis Weekly (2005-05-23)
More Articles from Hepatitis Weekly
- Chronic Hepatitis C
Hepatitis C core antigen may prevent liver injury in infected patients - Oncology
Aberrant proteins are a hallmark of primary liver cancer progression - Transplant Medicine
Ribavirin promotes liver fibrosis in HCV-positive kidney recipients - Virology
Viral interactions accelerate non-Hodgkin lymphoma progression - Addiction Medicine
Immunostains discern alcoholic steatohepatitis from nonalcoholic disease - Allergy & Immunology
Heterologous T cell immunity impacts the severity of hepatitis C infection - More from this issue of Hepatitis Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
