Transplant Medicine
Ribavirin promotes liver fibrosis in HCV-positive kidney recipients
Published in Hepatitis Weekly, May 23rd, 2005
According to published research from France, "in untreated hepatitis virus (HCV)-positive renal transplant patients, the rate of liver fibrosis progression is low. In contrast, in those treated by ribavirin monotherapy, liver fibrosis score increased significantly after only 1 year of ribavirin monotherapy. The aim of this study was to identify the factors that might contribute to accelerate liver fibrosis progression in this population."
"Eleven patients were included in the study. Intrahepatic transforming growth factor (TGF)-beta, interferon (IFN)-gamma, and interleukin (IL)-10...
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Source: Hepatitis Weekly (2005-05-23)
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