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Vaccine Development

Recombinant BCG containing hepatitis B surface antigens generates antibodies

Published in Hepatitis Weekly, May 23rd, 2005

Recombinant BCG containing hepatitis B surface antigens generates antibodies.

According to recent research from Brazil, "the Bacille Calmette Guerin (BCG), long valued for its role as a live vaccine for the prevention of tuberculosis, is being used as a recombinant delivery vehicle for foreign antigens, principally, for inducing long-lived specific humoral and cellular immunity. Hepatitis B and its sequelae are major public health problems. Although vaccines have been available for over 20 years the disease remains a significant global problem."

"Many factors contribute to vaccine failure to control hepatitis B, including attaining of adequate immune...

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