Published in Hepatitis Weekly, May 30th, 2005
"Rapamycin (Rapa), one of the newer immunosuppressants, has been found to control and prevent autoimmune features in animal models. This is the first report describing the successful control of post-transplant autoimmune hepatitis (AIH) with Rapa. Post-transplant AIH is diagnosed in the presence of raised transaminases, elevated immunoglobulin G, presence of autoantibodies, and histologic changes consistent with AIH on liver biopsy," scientists in the United States report.
"It may represent a recurrence of the original AIH that led to transplantation or present as a de novo...
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