Published in Hepatitis Weekly, June 6th, 2005
Study 1: Aberrant Pim-3 expression encourages hepatocellular carcinoma proliferation.
"Most cases of human hepatocellular carcinoma develop after persistent chronic infection with human hepatitis B virus or hepatitis C virus, and host responses are presumed to have major roles in this process. To recapitulate this process, we have developed the mouse model of hepatocellular carcinoma using hepatitis B virus surface antigen transgenic mice," scientists in Japan report.
"To identify the genes associated with hepatocarcinogenesis in this model, we compared the...
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