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Arteritis

Autoantibody repertoires in small- and medium-sized vessel vasculitides analyzed

Published in Hepatitis Weekly, June 27th, 2005

Scientists examined the autoantibody repertoires in small- and medium-sized vessel vasculitides.

According to recent research from France, "In order to identify new antibody reactivities, we have used a quantitative immunoblotting technique on extracts of normal human tissues to analyze the repertoires of serum IgM, serum IgG and purified IgG autoantibodies of patients with systemic vasculitides."

"Patients fulfilled the American College of Rheumatology and Chapel Hill criteria for the diagnosis of polyarteritis nodosa (PAN) (n=8), PAN related to hepatitis B virus (HBV) infection (n=5), Wegener's granulomatosis (WG) (n=6), microscopic polyangiitis...

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