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Adverse Drug Reaction

Patients with interferon-induced Graves disease fare better than others

Published in Hepatitis Weekly, July 4th, 2005

Patients with interferon-induced Graves disease fare better than others.

"An association between Graves disease (GD) and chronic hepatitis C (C-HC) has been observed both in the presence and the absence of recombinant interferon-alpha (rIFN-alpha) treatment," scientists in Italy report.

"rIFN-alpha-induced GD is characterized by suppressed thyroid-stimulating hormone levels; normal or elevated free triiodothyronine (FT3) and free thyroxine (FT4) values; the presence of thyroid peroxidase antibodies, antithyroglobulin antibodies, and thyroid receptor antibodies; and high iodine thyroid uptake. In contrast, GD developed during C-HC without rIFN-alpha...

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