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Antiviral Therapy

Combination therapy produces a sustained response in HCV cirrhosis

Published in Hepatitis Weekly, July 4th, 2005

Combination therapy produces a sustained response in HCV cirrhosis.

"Clearance of HCV before transplantation could avoid recurrence of hepatitis C in the liver allograft, thereby improving graft and patient survival. We report our experience with combined therapy for patients with HCV cirrhosis, including 12 patients with biopsy-proven liver cirrhosis (n=7) or previous cirrhotic complications (n=5)," scientists in Spain state.

"The Child-Pugh score was A in eight patients and B in four. Two patients had hepatocellular carcinoma. Genotype distribution was 1a (n=2), 1b (n=8) or 3 (n=1). Patients received peginterferon alpha 2b (1.5 mcg/kg once weekly)...

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