Chagas Disease

Researchers identify protein machinery of Chagas disease parasite

Published in Hepatitis Weekly, August 1st, 2005

A Howard Hughes Medical Institute investigator from Albany, New York, and an HHMI international research scholar from Buenos Aires, Argentina, have combined their expertise to identify two peculiar features of the protein-making machinery of the parasite that causes Chagas disease.

Their findings could help scientists develop a safe and effective drug for the disease, whose cardiac complications kill up to 30% of those infected.

The unusual structure of the ribosome, published online the week of July 4, 2005, in the Proceedings of the National Academy of Sciences, also suggests that the parasite has a unique scanning mechanism for translating...

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Source: Hepatitis Weekly (2005-08-01)

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