Diagnostics
Gp210-c terminal peptide antibody titers monitor primary billiary cirrhosis
Published in Hepatitis Weekly, August 1st, 2005
"The presence of antibodies to the 210-kDa glycoprotein of the nuclear pore complex (gp210) is highly indicative of primary biliary cirrhosis (PBC). However, the significance of anti-gp210 antibody titers for monitoring PBC remains unresolved," scientists writing in the Journal of Hepatology report.
"We used an enzyme-linked immunosorbent assay (ELISA) with a gp210 C-terminal peptide as an antigen to assess serum antibody titers in 71 patients with PBC. Patients were classified into three groups: group A in whom anti-gp210 titers were sustained at a high level, group...
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Source: Hepatitis Weekly (2005-08-01)
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