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Hepatitis Weekly

Susan Hasty, Publisher

Table of Contents . . . August 8th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Hepatitis Weekly | Other Publications

Endocrinology - Insulin resistance triggers hepatitis C-related liver steatosis and fibrosis

Hepatitis B Virus - Occult hepatitis B may hamper interferon in hepatitis C coinfected patients

Hepatitis C Therapy - Short courses of peginterferon clear hepatitis C genotypes 2 or 3

Rheumatology - Hepatitis C virus infection is not a cause of fibromyalgia

Transplant Medicine - Combination therapy is problematic after hepatitis C-related liver transplants

Allergy & Immunology - Innate immunity overwhelms adenoviral gene expression in the liver

Avian Influenza - International health entity stresses threat from Avian influenza has not ebbed

Awards - Virus research funded at Robarts by U.S.-based Howard Hughes Medical Institute

Business & Finance - Biopharma company announced financial results

Business & Finance - Medical company signs financing agreement with U.S. based investment fund

Cancer Treatment - Novel intrahepatic arterial chemotherapy introduced for hepatocellular carcinoma

Chronic Liver Disease - Liver iron overload in alcoholic end-stage liver disease affects other organs

Complementary & Alternative Medicine - The garlic component allicin prevents immune-mediated liver injury in mice

Diagnostics - Hepatitis C virus serotyping is useful for screening hemodialysis patients

Diagnostics - In situ hybridization can't detect hepatitis C RNA in all liver tissue samples

Diet and Nutrition - Peripheral blood antioxidants change as chronic hepatitis C activity increases

Disease Associations - HIV/HCV co-infection associated with diabetes

Drug Development - Enrollment complete in phase III DIRECT trial evaluating Infergen plus ribavirin

Fatty Liver Disease - Immune response to lipid peroxidation products predicts fibrosis progression

Fatty Liver Disease - Palmitic acid makes rodent liver cells self-destruct

Gastroenterology - Orocecal transit time is longer in non-alcoholic fatty liver disease patients

Hematology - FVII genes account for prothrombin prolongation in liver disease patients

Hematology - Suppressed hematopoiesis is persistent in chronic hepatitis C patients

Hepatic Cancer - Psychological request from patients for hemangioma surgery should be ignored

Hepatitis A - Universal immunization of toddlers in Israel reduces hepatitis A rates

Hepatitis B Prevention - Hepatitis B vaccine doses protect patients regardless of dialysis type

Hepatitis B Virus - Fulminant hepatitis strikes hepatitis B carriers with acute liver disease

Hepatitis B Virus - Hepatitis B basal core-promoter mutants stimulate cirrhosis and cancer

Hepatitis B Virus - Patients with chronic hepatitis B produce high levels of T cell activator

Hepatitis B Virus - Pro-inflammatory cytokine sustains liver injury in chronic hepatitis B

Hepatitis B Virus - Viremia fluctuates in chronic hepatitis B carriers

Hepatitis C - Pharma company provides update on hepatitis C virus R&D pipeline

Hepatitis C Virus - Agreement signed for celgosivir hepatitis C drug in phase 2 clinical development

Hepatitis C Virus - Interferons use IRES-dependent mechanisms to block hepatitis C replication

Hepatitis E Epidemiology - Hepatitis E infection produces unexplained acute hepatitis cases

Hepatocellular Cancer - Multi-step, incremental expansion method for radio frequency ablation examined

Hepatocellular Cancer - Treatment for hepatocellular carcinoma discussed

Liver Cancer - Expression of Wnt antagonists elevated in hepatoblastomas

Liver Cancer - Potential "weak link" between virus and liver cancer discovered

Liver Failure - Type and extent of hepatectomy drives post-surgical complications

Patents - U.K. patents granted covering siRNAs targeting VEGF and HCV

Patents - U.S. patent granted for interferons for treating hepatitis C, viral diseases

Vaccine Development - Pharma company receives grant to develop thermostable vaccines

Vaccine Development - U of Saskatchewan offered $5.6 million for research into vaccines for newborns

Veno-Occlusive Disease - C282Y allele is risk factor for hepatic veno-occlusive disease after HSCT

Virology - HIV values remain stable in hepatitis C coinfected patients on peginterferon

Virology - Hepatitis B virus genotype drives interferon efficacy

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