HIV/AIDS Research

Phase 1/2a study results indicate maraviroc is well tolerated

Published in Hepatitis Weekly, August 22nd, 2005

Results from early-stage clinical trials, presented at the 3rd International AIDS Society Conference on Pathogenesis and Treatment, indicate that maraviroc, an investigational drug for treatment of HIV/AIDS, was well-tolerated and decreased patient levels of HIV significantly in 10-day monotherapy studies in asymptomatic HIV-positive patients.

Maraviroc works through a different mechanism of action from currently marketed drugs. In a category of compounds known as "CCR5-antagonists," maraviroc blocks HIV from entering white blood cells, where the virus replicates, takes over the cell's DNA for its own reproduction, and ultimately destroys a patient's immune...

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Source: Hepatitis Weekly (2005-08-22)

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