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Hepatitis C Virus

Tarvacin phase I hepatitis C virus trial initiated

Published in Hepatitis Weekly, September 5th, 2005

Peregrine Pharmaceuticals, Inc., (PPHM) announced the initiation of a phase I antiviral study of Tarvacin, the company's first antiphospholipid therapy candidate.

The phase I study is an open-label, dose-escalation study in up to 32 adult patients with chronic hepatitis C virus (HCV) infection who either no longer respond to or failed standard therapy with pegylated interferon and ribavirin combination therapy.

The objectives of the trial are to evaluate safety, pharmacokinetics and viral load following a single intravenous infusion. The study is being conducted at Bach and Godofsky Infectious Diseases, the largest private infectious disease practice...

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