Autoimmune Disease
MICA-mimicking peptides show promise in explaining NKG2D-related autoimmunity
Published in Hepatitis Weekly, September 5th, 2005
"NKG2D is an activating receptor expressed on most of human natural killer (NK) cells, one of whose ligands is MICA. Based on the crystal structure of NKG2D-MICA complex, we synthesized three short peptides (P1, P2 and P3), mimicking functional alpha1 and alpha2 domain of MICA," scientists writing in the journal Peptides reported recently.
B. Zhang and associates at the University of Science and Technology of China in Anhui explained, "The inhibitory effects of three peptides on NK-92 cells, a human NK cell line against Hela cells...
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Source: Hepatitis Weekly (2005-09-05)
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