Drug Development

Hepatitis C clinical trial initiated to test NeuGene antisense compound

Published in Hepatitis Weekly, October 31st, 2005

AVI BioPharma, Inc., (AVII) announced the initiation of an exploratory safety and efficacy clinical trial using its proprietary NeuGene antisense compound AVI-4065.

The multicenter study will assess the safety, tolerability, pharmacokinetics and viral response to daily subcutaneous administration of AVI-4065 among healthy volunteers and patients with chronic active hepatitis C virus (HCV).

"There is a large, unmet medical need for effective HCV treatments, as the current treatment regimen is successful in less than half of the patients infected with genotype 1 HCV, the most common form of the virus in the U.S.," said Denis R. Burger, PhD, chief...

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Source: Hepatitis Weekly (2005-10-31)

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