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Cardiology

Divergent factors control hepatitis C-related cardiomyopathy

Published in Hepatitis Weekly, October 31st, 2005

Divergent factors control hepatitis C-related cardiomyopathy.

According to a study from Japan, "cardiomyopathy is a heart muscle disease with impaired stretch response that can result in severe heart failure and sudden death. A small proportion of hepatitis C virus (HCV)-infected patients may be predisposed to develop dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM)."

"The molecular mechanisms involved in the predisposition remain unknown due in part to the lack of information on their genetic background. Because the human leukocyte antigen (HLA) region has a pivotal role in controlling the susceptibility to HCV-induced liver...

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