Hepatitis C Complications

Hepatitis C is complicated by morphine withdrawal

Published in Hepatitis Weekly, November 14th, 2005

Researchers at the University of Pennsylvania have demonstrated that morphine withdrawal complicates hepatitis C by suppressing IFN-alpha-mediated immunity and enhancing virus replication.

The paper by Wang et al., "Morphine withdrawal enhances hepatitis C virus (HCV) replicon expression," appears in the November issue of The American Journal of Pathology and is accompanied by a commentary.

Hepatitis C virus (HCV) is common among intravenous drug users, with 70-80% of abusers infected in the United States. This high association has peaked interest in determining the effects of drug abuse, specifically opiates, on progression of the disease....

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Source: Hepatitis Weekly (2005-11-14)

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